ConCisE Scanner

Conserved Cis-Element Scanner: Genome-wide ortholog conserved Cis-element module search

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a) Enter basepairs ( to modify the default 10 KB sequence region )
b) Choose region : Upstream Downstream Upstream & Downstream
c) With respect to : First Exon Last Exon Gene

Extended query


Select binding sites for search against genes :

Matrix Name And Description
V$AARE.01 - Amino acid response element, ATF4 binding site
V$AHR.01 - Aryl hydrocarbon / dioxin receptor
V$AHRARNT.01 - Aryl hydrocarbon receptor / Arnt heterodimers
V$AHRARNT.02 - Aryl hydrocarbon / Arnt heterodimers, fixed core
V$AHRARNT.03 - DRE (dioxin response elements), XRE (xenobiotic response elements) bound by AHR/ARNT heterodimers
V$NXF_ARNT.01 - bHLH-PAS type transcription factors NXF/ARNT heterodimer
V$AIRE.01 - Autoimmune regulator
V$AP1.01 - Activator protein 1
V$AP1.02 - Activator protein 1
V$AP1.03 - Activator protein 1
V$AP1FJ.01 - Activator protein 1
V$BACH1.01 - BTB/POZ-bZIP transcription factor BACH1 forms heterodimers with the small Maf protein family
V$BACH2.01 - Bach2 bound TRE
V$MARE.01 - Maf response elements, half sites
V$MARE.02 - Binding sites for homodimers of large Maf-proteins
V$MARE.03 - Binding sites for heterodimers with small Maf-proteins
V$MARE_ARE.01 - Antioxidant response elements
V$NFE2.01 - NF-E2 p45
V$NFE2L2.01 - Nuclear factor (erythroid-derived 2)-like 2, NRF2
V$TCF11MAFG.01 - TCF11/MafG heterodimers, binding to subclass of AP1 sites
V$VMAF.01 - v-Maf
V$AP2.01 - Activator protein 2
V$AP2.02 - Activator protein 2 alpha
V$AP4.01 - Activator protein 4
V$AP4.02 - Activator protein 4
V$AP4.03 - Activator protein 4
V$LYL1_E12.01 - LYL1-E12 heterodimeric complex
V$PARAXIS.01 - Paraxis (TCF15), member of the Twist subfamily of Class B bHLH factors, forms heterodimers with E12
V$TAL1ALPHAE47.01 - Tal-1alpha/E47 heterodimer
V$TAL1BETAE47.01 - Tal-1beta/E47 heterodimer
V$TAL1BETAHEB.01 - Tal-1beta/HEB heterodimer
V$TAL1BETAITF2.01 - Tal-1beta/ITF-2 heterodimer
V$TH1E47.01 - Thing1/E47 heterodimer, TH1 bHLH member specific expression in a variety of embryonic tissues
V$AREB6.01 - AREB6 (Atp1a1 regulatory element binding factor 6)
V$AREB6.02 - AREB6 (Atp1a1 regulatory element binding factor 6)
V$AREB6.03 - AREB6 (Atp1a1 regulatory element binding factor 6)
V$AREB6.04 - AREB6 (Atp1a1 regulatory element binding factor 6)
V$MRF2.01 - Modulator recognition factor 2 (MRF2, ARID5B)
V$ARP1.01 - apolipoprotein AI regulatory protein 1
V$ATBF1.01 - AT-binding transcription factor 1
V$BARBIE.01 - Barbiturate-inducible element
V$BCL6.01 - POZ/zinc finger protein, transcriptional repressor, translocations observed in diffuse large cell lymphoma
V$BCL6.02 - POZ/zinc finger protein, transcriptional repressor, translocations observed in diffuse large cell lymphoma
V$BEL1.01 - Bel-1 similar region (defined in Lentivirus LTRs)
V$BNC.01 - Basonuclin, cooperates with USF1 in rDNA PolI transcription)
V$BRACH.01 - Brachyury
V$TBOX.01 - T-box transcription factor binding sites
V$TBX5.01 - T-Box factor 5 site (TBX5), mutations related to Holt-Oram syndrome
V$TBX6.01 - T-Box family transcription factor
V$BRN2.01 - Brn-2, POU-III protein class
V$BRN2.02 - Brn-2, POU-III protein class
V$BRN2.03 - Brn-2, POU-III protein class
V$BRN3.01 - Brn-3, POU-IV protein class
V$BRN3.02 - Brn-3, POU-IV protein class
V$BRN4.01 - POU domain transcription factor brain 4
V$BRN5.01 - Brn-5, POU-VI protein class (also known as emb and CNS-1)
V$KAISO.01 - Transcription factor Kaiso, ZBTB33
V$CABL.01 - Multifunctional c-Abl src type tyrosine kinase
V$CART1.01 - Cart-1 (cartilage homeoprotein 1)
V$XVENT2.01 - Xenopus homeodomain factor Xvent-2; early BMP signaling response
V$CDE.01 - Cell cycle-dependent element, CDF-1 binding site (CDE/CHR tandem elements regulate cell cycle dependent repression)
V$CDX1.01 - Intestine specific homeodomain factor CDX-1
V$CDX2.01 - Cdx-2 mammalian caudal related intestinal transcr. factor
V$CEBP.02 - CCAAT/enhancer binding protein
V$CEBPB.01 - CCAAT/enhancer binding protein beta
V$CHOP.01 - Heterodimers of CHOP and C/EBPalpha
V$CHOP.02 - Heterodimers of CHOP and C/EBPalpha
V$CHREBP_MLX.01 - Carbohydrate response element binding protein (CHREBP) and Max-like protein X (Mlx) bind as heterodimers to glucose-responsive promoters
V$CHR.01 - Cell cycle gene homology region (CDE/CHR tandem elements regulate cell cycle dependent repression)
V$NMP4.01 - NMP4 (nuclear matrix protein 4) / CIZ (Cas-interacting zinc finger protein)
V$CDP.01 - Cut-like homeodomain protein
V$CDP.02 - Transcriptional repressor CDP
V$CDPCR3.01 - Cut-like homeodomain protein
V$CDPCR3HD.01 - cut-like homeodomain protein
V$CLOX.01 - Clox
V$CUT2.01 - Cut repeat II
V$CMYB.01 - c-Myb, important in hematopoesis, cellular equivalent to avian myoblastosis virus oncogene v-myb
V$CMYB.02 - c-Myb, important in hematopoesis, cellular equivalent to avian myoblastosis virus oncogene v-myb
V$COMP1.01 - COMP1, cooperates with myogenic proteins in multicomponent complex
V$COUP.01 - COUP antagonizes HNF-4 by binding site competition or synergizes by direct protein - protein interaction with HNF-4
V$CP2.01 - CP2
V$CP2.02 - LBP-1c (leader-binding protein-1c), LSF (late SV40 factor), CP2, SEF (SAA3 enhancer factor)
V$ATF.01 - Activating transcription factor
V$ATF.02 - Activating transcription factor
V$ATF2.01 - Activating transcription factor 2
V$ATF6.02 - Activating transcription factor 6, member of b-zip family, induced by ER stress
V$CJUN_ATF2.01 - c-Jun/ATF2 heterodimers
V$CREB.01 - cAMP-responsive element binding protein
V$CREB.02 - cAMP-responsive element binding protein
V$CREB.03 - cAMP-response element-binding protein
V$CREB.04 - cAMP-response element binding protein
V$CREB1.01 - cAMP-responsive element binding protein 1
V$CREB2.01 - cAMP-responsive element binding protein 2
V$CREB2CJUN.01 - CRE-binding protein 2/c-Jun heterodimer
V$CREBP1.01 - cAMP-responsive element binding protein 1
V$CREBP1.02 - CRE-binding protein 1
V$CREBP1CJUN.01 - CRE-binding protein 1/c-Jun heterodimer
V$E4BP4.01 - E4BP4, bZIP domain, transcriptional repressor
V$TAXCREB.01 - Tax/CREB complex
V$TAXCREB.02 - Tax/CREB complex
V$VJUN.01 - v-Jun
V$DREAM.01 - Downstream regulatory element-antagonist modulator, Ca2+-binding protein of the neuronal calcium sensors family that binds DRE (downstream regulatory element) sites as a tetramer
V$NUDR.01 - NUDR (nuclear DEAF-1 related transcriptional regulator protein)
V$DICE.01 - Downstream Immunoglobulin Control Element, interacting factor: BEN (also termed Mus-TRD1 and WBSCR11)
V$DMP1.01 - Cyclin D-interacting myb-like protein, DMTF1 - cyclin D binding myb-like transcription factor 1
V$E2F.01 - E2F, involved in cell cycle regulation, interacts with Rb p107 protein
V$E2F.02 - E2F, involved in cell cycle regulation, interacts with Rb p107 protein
V$E2F.03 - E2F, involved in cell cycle regulation, interacts with Rb p107 protein
V$E2F1_DP1.01 - E2F-1/DP-1 heterodimeric complex
V$E2F1_DP2.01 - E2F-1/DP-2 heterodimeric complex
V$E2F4_DP1.01 - E2F-4/DP-1 heterodimeric complex
V$E2F4_DP2.01 - E2F-4/DP-2 heterodimeric complex
V$RB_E2F1_DP1.01 - RB/E2F-1/DP-1 heterotrimeric complex
V$E2.01 - BPV bovine papilloma virus regulator E2
V$E2.02 - Papilloma virus regulator E2
V$E4F.01 - GLI-Krueppel-related transcription factor, regulator of adenovirus E4 promoter
V$DELTAEF1.01 - deltaEF1
V$SIP1.01 - Smad-interacting protein
V$XBP1.01 - X-box-binding protein 1
V$ATF6.01 - Member of b-zip family, induced by ER damage/stress, binds to the ERSE in association with NF-Y
V$MAX.01 - Max
V$MYCMAX.01 - c-Myc/Max heterodimer
V$MYCMAX.02 - c-Myc/Max heterodimer
V$MYCMAX.03 - MYC-MAX binding sites
V$NMYC.01 - N-Myc
V$SREBP.01 - Sterol regulatory element binding protein 1 and 2
V$SREBP.02 - Sterol regulatory element binding protein
V$SREBP.03 - Sterol regulatory element binding protein
V$USF.01 - Upstream stimulating factor
V$USF.02 - Upstream stimulating factor
V$USF.03 - Upstream stimulating factor
V$USF.04 - Upstream stimulating factor 1/2
V$NFY.01 - Nuclear factor Y (Y-box binding factor)
V$NFY.02 - Nuclear factor Y (Y-box binding factor)
V$NFY.03 - Nuclear factor Y (Y-box binding factor)
V$CKROX.01 - Collagen krox protein (zinc finger protein 67 - zfp67)
V$EGR1.01 - Egr-1/Krox-24/NGFI-A immediate-early gene product
V$EGR1.02 - EGR1, early growth response 1
V$EGR2.01 - Egr-2/Krox-20 early growth response gene product
V$EGR3.01 - Early growth response gene 3 product
V$NGFIC.01 - Nerve growth factor-induced protein C
V$WT1.01 - Wilms Tumor Suppressor
V$BKLF.01 - Basic krueppel-like factor (KLF3)
V$EKLF.01 - Erythroid krueppel like factor (EKLF)
V$KKLF.01 - Kidney-enriched kruppel-like factor, KLF15
V$ER.01 - Estrogen receptor
V$ER.02 - Canonical palindromic estrogen response element (ERE)
V$ERR.01 - Estrogen related receptor
V$CETS1P54.01 - c-Ets-1(p54)
V$ELF2.01 - Ets - family member ELF-2 (NERF1a)
V$ELK1.01 - Elk-1
V$ELK1.02 - Elk-1
V$ETS1.01 - c-Ets-1 binding site
V$ETS2.01 - c-Ets-2 binding site
V$FLI.01 - ETS family member FLI
V$GABP.01 - GABP: GA binding protein
V$GABPB1.01 - GA repeat binding protein, beta 1)
V$NRF2.01 - Nuclear respiratory factor 2
V$PDEF.01 - Prostate-derived Ets factor
V$PEA3.01 - Polyomavirus enhancer A binding protein 3, ETV4 (Ets variant gene 4)
V$PU1.01 - Pu.1 (Pu120) Ets-like transcription factor identified in lymphoid B-cells
V$SPI1_PU1.01 - Spleen focus forming virus (SFFV) proviral integration oncogene Spi1/transcription factor PU.1
V$SPI1_PU1.02 - Spleen focus forming virus (SFFV) proviral integration oncogene Spi1/transcription factor PU.1
V$SPIB.01 - Spi-B transcription factor (Spi-1/PU.1 related)
V$EVI1.01 - Ecotropic viral integration site 1 encoded factor
V$EVI1.02 - Ecotropic viral integration site 1 encoded factor
V$EVI1.03 - Ecotropic viral integration site 1 encoded factor
V$EVI1.04 - Ecotropic viral integration site 1 encoded factor
V$EVI1.05 - Ecotropic viral integration site 1 encoded factor
V$EVI1.06 - Ecotropic viral integration site 1 encoded factor
V$EVI1.07 - Evi-1 zinc finger protein, carboxy-terminal zinc finger domain
V$MEL1.01 - MEL1 (MDS1/EVI1-like gene 1) DNA-binding domain 1
V$MEL1.02 - MEL1 (MDS1/EVI1-like gene 1) DNA-binding domain 2
V$MEL1.03 - MEL1 (MDS1/EVI1-like gene 1) DNA-binding domain 2
V$FAST1.01 - FAST-1 SMAD interacting protein
V$FAST1.02 - Forkhead box H1 (Foxh1)
V$FHXA.01 - Fork head homologous X binds DNA with a dual sequence specificity (FHXA and FHXB)
V$FHXB.01 - Fork head homologous X binds DNA with a dual sequence specificity (FHXA and FHXB)
V$FKHRL1.01 - Fkh-domain factor FKHRL1 (FOXO)
V$FREAC2.01 - Fork head related activator-2 (FOXF2)
V$FREAC3.01 - Fork head related activator-3 (FOXC1)
V$FREAC4.01 - Fork head related activator-4 (FOXD1)
V$FREAC7.01 - Fork head related activator-7 (FOXL1)
V$HFH1.01 - HNF-3/Fkh Homolog 1 (FOXQ1)
V$HFH2.01 - HNF-3/Fkh Homolog 2 (FOXD3)
V$HFH3.01 - HNF-3/Fkh Homolog 3 (FOXI1, Freac-6)
V$HFH8.01 - HNF-3/Fkh Homolog-8 (FOXF1)
V$HNF3B.01 - Hepatocyte Nuclear Factor 3beta (FOXA2)
V$ILF1.01 - Winged-helix transcription factor IL-2 enhancer binding factor (ILF), forkhead box K2 (FOXK2)
V$XFD1.01 - Xenopus fork head domain factor 1 (FoxA4a)
V$XFD2.01 - Xenopus fork head domain factor 2 (FoxI1a)
V$XFD3.01 - Xenopus fork head domain factor 3 (FoxA2a)
V$GAGA.01 - GAGA-Box
V$GATA.01 - GATA binding factor
V$GATA1.01 - GATA-binding factor 1
V$GATA1.02 - GATA-binding factor 1
V$GATA1.03 - GATA-binding factor 1
V$GATA1.04 - GATA-binding factor 1
V$GATA1.05 - GATA-binding factor 1
V$GATA1.06 - Complex of Lmo2 bound to Tal-1, E2A proteins, and GATA-1, half-site 2
V$GATA2.01 - GATA-binding factor 2
V$GATA2.02 - GATA-binding factor 2
V$GATA3.01 - GATA-binding factor 3
V$GATA3.02 - GATA-binding factor 3
V$LMO2COM.02 - complex of Lmo2 bound to Tal-1, E2A proteins, and GATA-1, half-site 2
V$GCM1.01 - Glial cells missing homolog 1, chorion-specific transcription factor GCMa
V$GFI1.01 - Growth factor independence 1 zinc finger protein acts as transcriptional repressor
V$GFI1.02 - Growth factor independence 1
V$GFI1B.01 - Growth factor independence 1 zinc finger protein Gfi-1B
V$GKLF.01 - Gut-enriched Krueppel-like factor
V$GKLF.02 - Gut-enriched Krueppel-like factor
V$GLI1.01 - Zinc finger transcription factor GLI1
V$GLI1.02 - Glioma-associated oncogene homolog 1
V$GLI2.01 - GLI-Kruppel family member GLI2
V$GLI3.01 - GLI-Kruppel family member GLI3
V$ZIC2.01 - Zinc finger transcription factor, Zic family member 2 (odd-paired homolog, Drosophila)
V$ARE.01 - Androgene receptor binding site
V$ARE.02 - Androgene receptor binding site
V$GRE.01 - Glucocorticoid receptor, C2C2 zinc finger protein binds glucocorticoid dependent to GREs
V$PRE.01 - Progesterone receptor binding site
V$GRHL3.01 - Grainyhead-like 3 (sister-of-mammalian grainyhead - SOM)
V$GZF1.01 - GDNF-inducible zinc finger protein 1 (ZNF336)
V$AML1.01 - AML1/CBFA2 Runt domain binding site
V$AML3.01 - Runt-related transcription factor 2 / CBFA1 (core-binding factor, runt domain, alpha subunit 1)
V$HAND2_E12.01 - Heterodimers of the bHLH transcription factors HAND2 (Thing2) and E12
V$HSF1.01 - Heat shock factor 1
V$HSF1.02 - Heat shock factor 1
V$HSF1.03 - Heat shock factor 1
V$HSF2.01 - Heat shock factor 2
V$HSF2.02 - Heat shock factor 2
V$HEN1.01 - HEN1
V$HEN1.02 - HEN1
V$HELT.01 - Hey-like bHLH-transcriptional repressor
V$HES1.01 - Drosophila hairy and enhancer of split homologue 1 (HES-1)
V$HES1.02 - Drosophila hairy and enhancer of split homologue 1 (HES-1)
V$HIC1.01 - Hypermethylated in cancer 1, transcriptional repressor containing five Kręppel-like C2H2 zinc fingers, for optimal binding multiple binding sites are required.
V$ARNT.01 - AhR nuclear translocator homodimers
V$CLOCK_BMAL1.01 - Binding site of Clock/BMAL1 heterodimer, NPAS2/BMAL1 heterodimer
V$DEC1.01 - Basic helix-loop-helix protein known as Dec1, Stra13 or Sharp2
V$DEC2.01 - Basic helix-loop-helix protein known as Dec2 or Sharp2
V$HIF1.01 - Hypoxia induced factor-1 (HIF-1)
V$HIF1.02 - Hypoxia inducible factor, bHLH / PAS protein family
V$HRE.01 - Hypoxia response elements, binding sites for HIF1alpha/ARNT heterodimers
V$MTBF.01 - Muscle-specific Mt binding site
V$HNF1.01 - Hepatic nuclear factor 1
V$HNF1.02 - Hepatic nuclear factor 1
V$HNF1.03 - Hepatic nuclear factor 1
V$HNF4.01 - Hepatic nuclear factor 4
V$HNF4.02 - Hepatic nuclear factor 4
V$HPF1.01 - HepG2-specific P450 2C factor-1 (ZNF83)
V$HNF6.01 - Liver enriched Cut - Homeodomain transcription factor HNF6 (ONECUT)
V$OC2.01 - CUT-homeodomain transcription factor Onecut-2
V$DLX1.01 - DLX-1, -2, and -5 binding sites
V$DLX3.01 - Distal-less 3 homeodomain transcription factor
V$DLX3.02 - Distal-less homeobox 3
V$EN1.01 - Homeobox protein engrailed (en-1)
V$HHEX.01 - Hematopoietically expressed homeobox, proline-rich homeodomain protein
V$MSX.01 - Homeodomain proteins MSX-1 and MSX-2
V$MSX2.01 - Muscle segment homeo box 2, homologue of Drosophila (HOX 8)
V$NOBOX.01 - Homeobox containing germ cell-specific transcription factor NOBOX
V$S8.01 - Binding site for S8 type homeodomains
V$HOX_PBX.01 - HOX/PBX binding sites
V$PBX1.01 - Homeo domain factor Pbx-1
V$PBX_HOXA9.01 - PBX - HOXA9 binding site
V$BARX2.01 - Barx2, homeobox transcription factor that preferentially binds to paired TAAT motifs
V$CRX.01 - Cone-rod homeobox-containing transcription factor / otx-like homeobox gene
V$GSC.01 - Vertebrate bicoid-type homeodomain protein Goosecoid
V$GSH1.01 - Homeobox transcription factor Gsh-1
V$GSH2.01 - Homeodomain transcription factor Gsh-2
V$HOX1-3.01 - Hox-1.3, vertebrate homeobox protein
V$HOXA9.01 - Member of the vertebrate HOX - cluster of homeobox factors
V$HOXB9.01 - Abd-B-like homeodomain protein Hoxb-9
V$HOXC13.01 - Homeodomain transcription factor HOXC13
V$NANOG.01 - Homeobox transcription factor Nanog
V$OTX2.01 - Homeodomain transcription factor Otx2 (homolog of Drosophila orthodenticle)
V$PCE1.01 - Photoreceptor conserved element 1
V$PHOX2.01 - Phox2a (ARIX) and Phox2b
V$PTX1.01 - Pituitary Homeobox 1 (Ptx1, Pitx-1)
V$MEIS1A_HOXA9.01 - Meis1a and Hoxa9 form heterodimeric binding complexes on target DNA
V$MEIS1B_HOXA9.01 - Meis1b and Hoxa9 form heterodimeric binding complexes on target DNA
V$IK1.01 - Ikaros 1, potential regulator of lymphocyte differentiation
V$IK2.01 - Ikaros 2, potential regulator of lymphocyte differentiation
V$IK3.01 - Ikaros 3, potential regulator of lymphocyte differentiation
V$LYF1.01 - LyF-1 (Ikaros 1), enriched in B and T lymphocytes
V$INSM1.01 - Zinc finger protein insulinoma-associated 1 (IA-1) functions as a transcriptional repressor
V$IRF1.01 - Interferon regulatory factor 1
V$IRF2.01 - Interferon regulatory factor 2
V$IRF3.01 - Interferon regulatory factor 3 (IRF-3)
V$IRF4.01 - Interferon regulatory factor (IRF)-related protein (NF-EM5, PIP, LSIRF, ICSAT)
V$IRF4.02 - Interferon regulatory factor 4
V$IRF7.01 - Interferon regulatory factor 7 (IRF-7)
V$ISRE.01 - Interferon-stimulated response element
V$LEF1.01 - TCF/LEF-1, involved in the Wnt signal transduction pathway
V$LEF1.02 - TCF/LEF-1, involved in the Wnt signal transduction pathway
V$LHX3.01 - Homeodomain binding site in LIM/Homeodomain factor LHX3
V$LHX3.02 - LIM-homeodomain transcription factor LHX3
V$LMX1B.01 - LIM-homeodomain transcription factor
V$TAACC.01 - Lentiviral TATA upstream element
V$MAZ.01 - Myc associated zinc finger protein (MAZ)
V$MAZR.01 - MYC-associated zinc finger protein related transcription factor
V$AMEF2.01 - Myocyte enhancer factor
V$HMEF2.01 - Myocyte enhancer factor
V$MEF2.01 - Myogenic enhancer factor 2
V$MEF2.02 - Myogenic MADS factor MEF-2
V$MEF2.03 - Myogenic MADS factor MEF-2
V$MEF2.04 - Myogenic MADS factor MEF-2
V$MEF2.05 - MEF2
V$MEF2.06 - Myocyte-specific enhancer factor 2
V$MEF2.07 - Myocyte-specific enhancer factor 2
V$MMEF2.01 - Myocyte enhancer factor
V$RSRFC4.01 - Related to serum response factor, C4
V$RSRFC4.02 - Related to serum response factor, C4
V$SL1.01 - Member of the RSRF (related to serum response factor) protein family from Xenopus laevis
V$MEF3.01 - MEF3 binding site, present in skeletal muscle-specific transcriptional enhancers
V$MUSCLE_INI.01 - Muscle Initiator Sequence
V$MUSCLE_INI.02 - Muscle Initiator Sequence
V$MIT.01 - MIT (microphthalmia transcription factor) and TFE3
V$MOK2.01 - Ribonucleoprotein associated zinc finger protein MOK-2 (mouse)
V$MOK2.02 - Ribonucleoprotein associated zinc finger protein MOK-2 (human)
V$MTF-1.01 - Metal transcription factor 1, MRE
V$E47.01 - MyoD/E47 and MyoD/E12 dimers
V$E47.02 - TAL1/E47 dimers
V$LMO2COM.01 - Complex of Lmo2 bound to Tal-1, E2A proteins, and GATA-1, half-site 1
V$MYF5.01 - Myf5 myogenic bHLH protein
V$MYOD.01 - Myoblast determination gene product
V$MYOD.02 - Myoblast determining factor
V$MYOGENIN.01 - Myogenic bHLH protein myogenin (myf4)
V$MYOGENIN.02 - Myogenic bHLH protein myogenin (myf4)
V$TAL1_E2A.01 - Complex of Lmo2 bound to Tal-1, E2A proteins, and GATA-1, half-site 1
V$MYOGNF1.01 - Myogenin / nuclear factor 1 or related factors
V$MYT1.01 - MyT1 zinc finger transcription factor involved in primary neurogenesis
V$MYT1.02 - MyT1 zinc finger transcription factor involved in primary neurogenesis
V$MYT1L.01 - Myelin transcription factor 1-like, neuronal C2HC zinc finger factor 1
V$MZF1.01 - Myeloid zinc finger protein MZF1
V$MZF1.02 - Myeloid zinc finger protein MZF1
V$MZF1.03 - Myeloid zinc finger protein MZF1
V$NEUROD1.01 - DNA binding site for NEUROD1 (BETA-2 / E47 dimer)
V$NEUROG.01 - Neurogenin 1 and 3 (ngn1/3) binding sites
V$NF1.01 - Nuclear factor 1
V$NF1.02 - Nuclear factor 1 (CTF1)
V$NF1.03 - Non-palindromic nuclear factor I binding sites
V$NFAT.01 - Nuclear factor of activated T-cells
V$NFAT5.01 - Nuclear factor of activated T-cells 5
V$CREL.01 - c-Rel
V$HIVEP1.01 - ZAS domain transcription factor: human immunodeficiency virus type 1 enhancer-binding protein-1 (HIVEP1), major histocompatibility complex-binding protein-1 (MBP-1), positive regulatory domain II-binding factor 1 (PRDII-BF1)
V$NFKAPPAB.01 - NF-kappaB
V$NFKAPPAB.02 - NF-kappaB
V$NFKAPPAB.03 - NF-kappaB
V$NFKAPPAB50.01 - NF-kappaB (p50)
V$NFKAPPAB65.01 - NF-kappaB (p65)
V$HMX2.01 - Hmx2/Nkx5-2 homeodomain transcription factor
V$HMX2.02 - Hmx2/Nkx5-2 homeodomain transcription factor
V$HMX3.01 - H6 homeodomain HMX3/Nkx5.1 transcription factor
V$HMX3.02 - Hmx3/Nkx5-1 homeodomain transcription factor
V$NKX25.01 - Homeo domain factor Nkx-2.5/Csx, tinman homolog, high affinity sites
V$NKX25.02 - Homeo domain factor Nkx-2.5/Csx, tinman homolog low affinity sites
V$NKX25.03 - Homeodomain factor Nkx-2.5/Csx
V$NKX31.01 - Prostate-specific homeodomain protein NKX3.1
V$NKX32.01 - Homeodomain protein NKX3.2 (BAPX1, NKX3B, Bagpipe homolog)
V$OLF1.01 - Olfactory neuron-specific factor
V$OLF1.02 - Olfactory neuron-specific factor
V$COUP.02 - Chicken ovalbumin upstream promoter (COUP-TF), DR0 sites
V$HNF4.03 - Hepatic nuclear factor 4, DR1 sites
V$PNR.01 - Photoreceptor-specific nuclear receptor subfamily 2, group E, member 3 (Nr2e3)
V$TR2_TR4.01 - DR1 binding sites for TR2 homodimers or TR2/TR4 heterodimers
V$TR4.02 - TR4 homodimer, DR1 site
V$NRF1.01 - Nuclear respiratory factor 1 (NRF1), bZIP transcription factor that acts on nuclear genes encoding mitochondrial proteins
V$NRL.01 - Neural retinal basic leucine zipper factor (bZIP)
V$NRSE.01 - Neural-restrictive-silencer-element
V$NRSF.01 - Neuron-restrictive silencer factor
V$ROAZ.01 - Rat C2H2 Zn finger protein involved in olfactory neuronal differentiation
V$OCT.01 - Octamer binding site (OCT1/OCT2)
V$OCT1.01 - Octamer-binding factor 1
V$OCT1.02 - Octamer-binding factor 1
V$OCT1.04 - Octamer-binding factor 1
V$OCT1.05 - Octamer-binding factor 1
V$OCT1.06 - Octamer-binding factor 1
V$OCT3_4.01 - POU domain, class 5, transcription factor 1
V$TST1.01 - POU-factor Tst-1/Oct-6
V$OCT1P.01 - Octamer-binding factor 1, POU-specific domain
V$P53.01 - Tumor suppressor p53
V$P53.02 - Tumor suppressor p53 (5' half site)
V$P53.03 - Tumor suppressor p53 (3' half site)
V$P53.04 - Tumor suppressor p53
V$P53.05 - Tumor suppressor p53
V$P53.06 - Tumor suppressor p53
V$DBP.01 - Albumin D-box binding protein
V$PAX1.01 - Pax1 paired domain protein, expressed in the developing vertebral column of mouse embryos
V$PAX2.01 - Zebrafish PAX2 paired domain protein
V$PAX3.01 - Pax-3 paired domain protein, expressed in embryogenesis, mutations correlate to Waardenburg Syndrome
V$PAX3.02 - Pax-3 paired domain protein
V$PAX4.01 - Pax-4 homeodomain binding site, together with PAX-6 involved in pancreatic development
V$PAX5.01 - B-cell-specific activating protein
V$PAX5.02 - B-cell-specific activating protein
V$PAX5.03 - PAX5 paired domain protein
V$PAX9.01 - Zebrafish PAX9 binding sites
V$PAX4_PD.01 - PAX4 paired domain binding site
V$PAX6.01 - Pax-6 paired domain binding site
V$PAX6.02 - PAX6 paired domain and homeodomain are required for binding to this site
V$PAX6.03 - Pax-6 paired domain binding site
V$PAX6.04 - PAX6 paired domain binding site
V$PAX8.01 - PAX 2/5/8 binding site
V$PBX1_MEIS1.01 - Binding site for a Pbx1/Meis1 heterodimer
V$PBX1_MEIS1.02 - Binding site for a Pbx1/Meis1 heterodimer
V$PBX1_MEIS1.03 - Binding site for a Pbx1/Meis1 heterodimer
V$ACAAT.01 - Avian C-type LTR CCAAT box
V$CAAT.01 - Cellular and viral CCAAT box
V$ISL1.01 - Pancreatic and intestinal lim-homeodomain factor
V$PDX1.01 - Pdx1 (IDX1/IPF1) pancreatic and intestinal homeodomain TF
V$PPARA.01 - PPAR/RXR heterodimers
V$PPAR_RXR.01 - PPAR/RXR heterodimers
V$PPAR_RXR.02 - PPAR/RXR heterodimers
V$PIT1.01 - Pit1, GHF-1 pituitary specific pou domain transcription factor
V$PLAG1.01 - Pleomorphic adenoma gene (PLAG) 1, a developmentally regulated C2H2 zinc finger protein
V$PLZF.01 - Promyelocytic leukemia zink finger (TF with nine Krueppel-like zink fingers)
V$PPARG.01 - Pal3 motif, bound by a PPAR-gamma homodimer
V$BLIMP1.01 - Transcriptional repressor B lymphocyte-induced maturation protein-1 (Blimp-1, prdm1)
V$PRDM1.01 - PRDI binding factor 1
V$PTF1.01 - PTF1 binding sites are bipartite with an E-box and a TC-box (RBP-J/L) spaced one helical turn apart
V$PURALPHA.01 - Purine-rich element binding protein A
V$PXRCAR.01 - Halfsite of PXR (pregnane X receptor)/RXR resp. CAR (constitutive androstane receptor)/RXR heterodimer binding site
V$RAR.01 - Retinoic acid receptor, member of nuclear receptors
V$RAR.02 - Retinoic acid receptor, member of nuclear receptors, DR5 site
V$RTR.01 - Retinoid receptor-related testis-associated receptor (GCNF/RTR)
V$BRIGHT.01 - Bright, B cell regulator of IgH transcription
V$RBPJK.01 - Mammalian transcriptional repressor RBP-Jkappa/CBF1
V$RBPJK.02 - Mammalian transcriptional repressor RBP-Jkappa/CBF1
V$CLTR_CAAT.01 - Mammalian C-type LTR CCAAT box
V$EBVR.01 - Epstein-Barr virus transcription factor R
V$NBRE.01 - Monomers of the nur subfamily of nuclear receptors (nur77, nurr1, nor-1)
V$REV-ERBA.01 - Orphan nuclear receptor rev-erb alpha (NR1D1)
V$REV-ERBA.02 - Orphan nuclear receptor rev-erb alpha (NR1D1), monomer binding site
V$REV-ERBA.03 - Orphan nuclear receptor rev-erb alpha (NR1D1), homodimer DR2 binding site
V$RORA.01 - RAR-related orphan receptor alpha
V$RORA1.01 - RAR-related orphan receptor alpha1
V$RORA2.01 - RAR-related orphan receptor alpha2
V$RORGAMMA.01 - RAR-related orphan receptor gamma
V$T3R.01 - vErbA, viral homolog of thyroid hormone receptor alpha1
V$TR2.01 - Nuclear hormone receptor TR2, half site
V$TR4.01 - Nuclear hormone receptor TR4 homodimer binding site
V$VERBA.01 - vErbA, viral homolog of thyroid hormone receptor alpha1
V$RP58.01 - Zinc finger protein RP58 (ZNF238), associated preferentially with heterochromatin
V$RREB1.01 - Ras-responsive element binding protein 1
V$RU49.01 - Zinc finger transcription factor RU49 (zinc finger proliferation 1 - Zipro 1). RU49 exhibits a strong preference for binding to tandem repeats of the minimal RU49 consensus binding site.
V$SMARCA3.01 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3
V$SMARCA3.02 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3
V$CAR_RXR.01 - Constitutive androstane receptor / retinoid X receptor heterodimer, DR4 sites
V$FXRE.01 - Farnesoid X - activated receptor (RXR/FXR dimer)
V$LXRE.01 - Nuclear receptor involved in the regulation lipid homeostasis
V$LXRE.02 - Highly conserved DR1 element selected by LXRbeta/RXR heterodimers
V$PXR_RXR.01 - Pregnane X receptor / retinoid X receptor heterodimer, DR4 sites
V$RAR_RXR.01 - Retinoic acid receptor / retinoid X receptor heterodimer, DR1 sites
V$RAR_RXR.02 - Retinoic acid receptor / retinoid X receptor heterodimer, DR2 sites
V$RAR_RXR.03 - Retinoic acid receptor / retinoid X receptor heterodimer, DR5 sites
V$RXR_RXR.01 - Retinoid X receptor homodimer, DR1 sites
V$THR.01 - THR/RXR heterodimer and THR homodimer DR4 binding sites
V$VDR_RXR.01 - VDR/RXR Vitamin D receptor RXR heterodimer site
V$VDR_RXR.02 - VDR/RXR Vitamin D receptor RXR heterodimer site
V$VDR_RXR.03 - Bipartite binding site of VDR/RXR heterodimers without a spacer between directly repeated motifs
V$VDR_RXR.04 - Bipartite binding site of VDR/RXR heterodimers: 2 spacer nucleotides between the two directly repeated motifs
V$VDR_RXR.05 - Bipartite binding site of VDR/RXR heterodimers: 3 spacer nucleotides between the two directly repeated motifs
V$VDR_RXR.06 - Bipartite binding site of VDR/RXR heterodimers: 4 spacer nucleotides between the two directly repeated motifs
V$SATB1.01 - Special AT-rich sequence-binding protein 1, predominantly expressed in thymocytes, binds to matrix attachment regions (MARs)
V$FTF.01 - Alpha (1)-fetoprotein transcription factor (FTF), liver receptor homologue-1 (LRH-1)
V$SF1.01 - SF1 steroidogenic factor 1
V$SIX3.01 - SIX3 / SIXdomain (SD) and Homeodomain (HD) transcription factor
V$SMAD.01 - Sma- and Mad-related proteins
V$SMAD3.01 - Smad3 transcription factor involved in TGF-beta signaling
V$SMAD4.01 - Smad4 transcription factor involved in TGF-beta signaling
V$PSE.01 - Proximal sequence element (PSE) of RNA polymerase II-transcribed snRNA genes
V$PSE.02 - Proximal sequence element (PSE) of RNA polymerase III-transcribed genes
V$HBP1.01 - HMG box-containing protein 1
V$HMGA.01 - HMGA family of architectural transcription factors (HMGA1, HMGA2)
V$HMGIY.01 - HMGI(Y) high-mobility-group protein I (Y), architectural transcription factor organizing the framework of a nuclear protein-DNA transcriptional complex
V$SOX5.01 - Sox-5
V$SOX9.01 - SOX (SRY-related HMG box)
V$SOX9.02 - SRY (sex-determining region Y) box 9
V$SRY.01 - Sex-determining region Y gene product
V$BTEB3.01 - Basic transcription element (BTE) binding protein, BTEB3, FKLF-2
V$GC.01 - GC box elements
V$SP1.01 - Stimulating protein 1 SP1, ubiquitous zinc finger transcription factor
V$SP1.02 - Stimulating protein 1, ubiquitous zinc finger transcription factor
V$SP2.01 - Sp2, member of the Sp/XKLF transcription factors with three C2H2 zinc fingers in a conserved carboxyl-terminal domain
V$TIEG.01 - TGFbeta-inducible early gene (TIEG) / Early growth response gene alpha (EGRalpha)
V$SRF.01 - Serum response factor
V$SRF.02 - Serum response factor
V$SRF.03 - Serum responsive factor
V$STAF.01 - Se-Cys tRNA gene transcription activating factor
V$STAF.02 - Se-Cys tRNA gene transcription activating factor
V$ZNF76_143.01 - ZNF143 is the human ortholog of Xenopus Staf, ZNF76 is a DNA binding protein related to ZNF143 and Staf
V$STAT.01 - Signal transducers and activators of transcription
V$STAT1.01 - Signal transducer and activator of transcription 1
V$STAT3.01 - Signal transducer and activator of transcription 3
V$STAT5.01 - STAT5: signal transducer and activator of transcription 5
V$STAT6.01 - STAT6: signal transducer and activator of transcription 6
V$MEIS1.01 - Binding site for monomeric Meis1 homeodomain protein
V$TGIF.01 - TG-interacting factor belonging to TALE class of homeodomain factors
V$ATATA.01 - Avian C-type LTR TATA box
V$LTATA.01 - Lentivirus LTR TATA box
V$MTATA.01 - Muscle TATA box
V$TATA.01 - Cellular and viral TATA box elements
V$TATA.02 - Mammalian C-type LTR TATA box
V$TCF11.01 - TCF11/KCR-F1/Nrf1 homodimers
V$HLF.01 - Hepatic leukemia factor
V$TEAD.01 - TEA domain-containing factors, transcriptional enhancer factors 1,3,4,5
V$TEF.01 - Thyrotrophic embryonic factor
V$TEF1.01 - TEF-1 related muscle factor
V$TEF_HLF.01 - Thyrotrophic embryonic factor / hepatic leukemia factor
V$GTF3R4.01 - GTF2I-like repeat 4 of GTF3
V$TFII-IR4.01 - GTF2I repeat 4 of the general transcription factor II, i (GTF2I)
V$THAP1.01 - THAP domain containing, apoptosis associated protein
V$TTF1.01 - Thyroid transcription factor-1 (TTF1) binding site
V$VBP.01 - PAR-type chicken vitellogenin promoter-binding protein
V$VMYB.01 - v-Myb
V$VMYB.02 - v-Myb
V$VMYB.03 - v-Myb, viral myb variant from transformed BM2 cells
V$VMYB.04 - v-Myb, AMV v-myb
V$VMYB.05 - v-Myb, variant of AMV v-myb
V$WHN.01 - Winged helix protein, involved in hair keratinization and thymus epithelium differentiation
V$MIF1.01 - MIBP-1 / RFX1 complex
V$RFX1.01 - X-box binding protein RFX1
V$RFX1.02 - X-box binding protein RFX1
V$XBOX.01 - Motif bound by regulatory factor X (RFX) proteins
V$YY1.01 - Yin and Yang 1
V$YY1.02 - Yin and Yang 1 repressor sites
V$ZBP89.01 - Zinc finger transcription factor ZBP-89
V$ZF9.01 - Core promoter-binding protein (CPBP) with 3 Krueppel-type zinc fingers
V$ZNF202.01 - Transcriptional repressor, binds to elements found predominantly in genes that participate in lipid metabolism
V$ZNF219.01 - Kruppel-like zinc finger protein 219
V$ZNF35.01 - Human zinc finger protein ZNF35
V$ZF5.01 - Zinc finger / POZ domain transcription factor
V$ZID.01 - Zinc finger with interaction domain
V$SZF1.01 - SZF1, hematopoietic progenitor-restricted KRAB-zinc finger protein
V$ZBRK1.01 - Transcription factor with 8 central zinc fingers and an N-terminal KRAB domain
I$ADF1.01 - Adf-1
I$BRCZ1.01 - Broad-Complex Z1 Zinc Finger isoform
I$BRCZ2.01 - Broad-Complex Z2 Zinc Finger isoform
I$BRCZ4.01 - Broad-Complex Z4 Zinc Finger isoform
I$CAD.01 - Drosophila homeodomain protein caudal, vertebrate homolog cdx
I$CF1.01 - chorion factor 1, homologous to retinoid X receptor
I$CF2II.01 - CF2-II, Zinc finger splice variant II
I$CF2II.02 - CF2-II, Zinc finger splice variant II
I$CROC.01 - Crocodile regulator of head development, member of fork head domain protein family
I$DL.01 - Dorsal, protein for dorso-ventral axis formation, homologous to vertebrate c-rel
I$DL.02 - Dorsal, protein for dorso-ventral axis formation, homologous to vertebrate c-rel
I$E74A.01 - E74A early ecdysone-inducible gene in onset of Drosophila metamorphosis
I$ELF1.01 - Drosophila Elf-1 (NTF-1), vertebrate homolog CP2 (human, mouse)
I$GCM.01 - glial cells missing
I$HAIRY.01 - Hairy, transcriptional repressor
I$BCD.01 - Bicoid, maternal effect gene in drosophila embryogenesis
I$DFD.01 - Deformed, homeotic gene in drosophila development
I$FTZ.01 - fushi tarazu, involved in body segmentation of the drosophila embryo
I$K50_HD.01 - K50 type homeodomain site selected with drosophila orthodenticle (OTD) homeodomain
I$HSF.01 - heat shock factor (Drosophila)
I$HSF.02 - heat shock factor (Drosophila)
I$HSF.03 - heat shock factor (Drosophila)
I$HSF.04 - heat shock factor (Drosophila)
I$HB.01 - Hunchback, early maternal and zygotic zinc finger gene, activated by bicoid
I$HB.02 - Hunchback, early maternal and zygotic zinc finger gene, activated by bicoid
I$KNI.01 - Drosophila gap gene knirps, involved in embryonic segmentation
I$KR.01 - Krueppel, zinc finger protein, involved in body segmentation of the drosophila embryo
I$PHO.01 - PHO (pleiohomeotic) and PHO-like, polycomp group proteins (PcG) binding to PREs (polycomb group response elements)
I$SN.01 - Snail zinc finger protein, involved in dorso-ventral patterning
I$SN.02 - Snail zinc finger protein, involved in dorso-ventral patterning
I$STAT.01 - signal transducers and activators of transcription
I$SUH.01 - Suppressor of Hairless, linked to notch pathway
I$DSX.01 - Drosophila Doublesex (DSX), involved in sex determination)
I$DTCF.01 - drosophila T-cell factor, homolog of TCF/LEF, interacts with Armadillo (b-Catenin homolog
I$TLL.01 - Drosophila gap gene tailless, involved in embryonic segmentation
I$TTK.01 - Tramtrack 69K zinc finger protein, binding sites in eve gene
I$GAF.01 - GAGA factor encoded by the Trithorax-like gene (Trl)
I$PAX6_HD.01 - Drosophila PAX6 P3 homeodomain binding site
I$PRD_HD.01 - Drosophila paired homeodomain
I$ZESTE.01 - Zeste transvection gene product
 Putative target analysis and annotation is done using the L2L Analysis Tool (Newman and Weiner, 2005) which uses published gene expression data and Gene Ontology annotations.  
 Developed by the Division of BioMedical Informatics
 Copyright © 2002-2005 Cincinnati Children's Hospital Medical Center
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